6Suppliers
12Customers
3Debt Items
20Related Chains

Source-Backed Evidence Depth

Karyopharm Therapeutics Inc. (KPTI) is shown with relationship data already present in ChainSifter's database. Counts below come from stored supply-chain records and filing/source URLs where available; missing source URLs are not filled in or estimated.

31Total relationships
4Distinct source URLs
19High confidence
0.829Average confidence
2026-10-28Latest database update
ChainSifter does not infer unreported suppliers, customers, ownership, acquisitions, debt exposure, revenue dependency, or future supply-chain events on this public page.

Karyopharm Therapeutics Inc. Suppliers

TickerNameConfidenceEvidence
THIRD-PARTY-CONTRACT-MANUFACTURERS THIRD-PARTY-CONTRACT-MANUFACTURERS 92% We currently rely, and expect to continue to rely, on third-party contract manufacturers to manufacture our products and product candidates for our commercial and clinical use.
ADVERTISING-AGENCIES ADVERTISING-AGENCIES 90% We employ third-party vendors, such as advertising agencies, market research firms and suppliers of marketing and other sales support-related services, to assist with our commercial activities.
MARKET-RESEARCH-FIRMS MARKET-RESEARCH-FIRMS 90% We employ third-party vendors, such as advertising agencies, market research firms and suppliers of marketing and other sales support-related services, to assist with our commercial activities.
GLTO Damora Therapeutics, Inc. 72% Reciprocal relationship from GLTO graph: Reciprocal relationship from KPTI graph: Reciprocal relationship from GLTO graph: 026, we had an accumulated deficit of $515.1 million. We expect to continue …
ORANY ORANY 72% respond to the product candidate to obtain pre-market approval (“PMA”) simultaneously with approval of the therapeutic product candidate. The PMA process, including the gathering of clinical and prec…
ORANY ORANY 72% Reciprocal relationship from ORANY graph: Reciprocal relationship from KPTI graph: Reciprocal relationship from ORANY graph: Reciprocal relationship from KPTI graph: respond to the product candidate …

Karyopharm Therapeutics Inc. Customers

TickerNameConfidenceEvidence
ANTENGENE-THERAPEUTICS-LIMITED ANTENGENE-THERAPEUTICS-LIMITED 90% In prior periods, we entered into license agreements with Berlin-Chemie AG, an affiliate of the Menarini Group ("Menarini"), and Antengene Therapeutics Limited ("Antengene"), both of which are accoun…
BERLIN-CHEMIE-AG BERLIN-CHEMIE-AG 90% In prior periods, we entered into license agreements with Berlin-Chemie AG, an affiliate of the Menarini Group ("Menarini"), and Antengene Therapeutics Limited ("Antengene"), both of which are accoun…
PHARMACY-BENEFIT-MANAGERS PHARMACY-BENEFIT-MANAGERS 85% A number of states, for example, require drug manufacturers and other entities in the drug supply chain, including health carriers, pharmacy benefit managers, wholesale distributors, to disclose info…
KKR KKR & Co. Inc. 72% Reciprocal relationship from KKR graph: Reciprocal relationship from KPTI graph: Reciprocal relationship from KKR graph: Reciprocal relationship from KPTI graph: ternatives to achieve our business ob…
KKR KKR & Co. Inc. 72% ternatives to achieve our business objectives. If we are unable to raise sufficient capital or to enter into strategic alternatives on acceptable terms to meet our needs, we may be forced to delay, r…
ORANY ORANY 72% respond to the product candidate to obtain pre-market approval (“PMA”) simultaneously with approval of the therapeutic product candidate. The PMA process, including the gathering of clinical and prec…
ORANY ORANY 72% Reciprocal relationship from ORANY graph: Reciprocal relationship from KPTI graph: respond to the product candidate to obtain pre-market approval (“PMA”) simultaneously with approval of the therapeut…
ANTENGENE-CORPORATION-CO-LTD ANTENGENE-CORPORATION-CO-LTD 62% ecoverability of our inventory each reporting period and write-down any inventory that has become obsolete, that has a cost basis in excess of its estimated realizable value, or that is not expected …
CHANGE-MENARINI-GROUP CHANGE-MENARINI-GROUP 62% n 2025. This increase was primarily attributable to an unusually high product return reserve recorded in the prior-year period, which reduced net revenue in that period, as well as lower gross-to-net…
HEALTHCARE-ROYALTY-MANAGEMENT-LLC HEALTHCARE-ROYALTY-MANAGEMENT-LLC 62% ternatives to achieve our business objectives. If we are unable to raise sufficient capital or to enter into strategic alternatives on acceptable terms to meet our needs, we may be forced to delay, r…
HEALTHCARE-ROYALTY-PARTNERS HEALTHCARE-ROYALTY-PARTNERS 62% ortized cost basis. Any impairment that is not related to a credit loss is recognized in other comprehensive income (loss). Changes in the allowance for credit losses are recorded as a provision for …
MENARINI-GROUP MENARINI-GROUP 62% nue in effect on a product-by-product, country-by-country basis until the later of the tenth anniversary of the first commercial sale of the applicable product in such country or the expiration of sp…

Karyopharm Therapeutics Inc. Debt Obligations

InstrumentDescriptionConfidenceEvidence
KPTI-DEBT-10565 Warrants outstanding: 0.0001 90% xbrl warrant detail from xbrl 2026-03-31.
KPTI-DEBT-10566 Xbrl Convertible 90% xbrl convertible detail from xbrl 2025-12-31.
KPTI-DEBT Debt stack $169.3M 90% Market cache reports total debt of $169.3M.

Karyopharm Therapeutics Inc. Acquisitions

No acquisitions on recordNo completed or pending acquisitions found in our database for Karyopharm Therapeutics Inc..

Karyopharm Therapeutics Inc. Ownership

HolderNameConfidenceEvidence
KPTI-OWNER-VANGUARD-GROUP-INC Vanguard Group Inc 95% 13F/ownership overlay lists Vanguard Group Inc; shares held 559,619; ownership 3.05%; value $3.1M; as of 2025-12-31.
KPTI-OWNER-BRAIDWELL-LP Braidwell LP 95% 13F/ownership overlay lists Braidwell LP ; shares held 303,370; ownership 1.65%; value $1.7M; as of 2025-12-31.
KPTI-OWNER-ADAGE-CAPITAL-PARTNERS-GP-L-L-C Adage Capital Partners GP L.L.C. 95% 13F/ownership overlay lists Adage Capital Partners GP L.L.C.; shares held 421,322; ownership 2.30%; value $2.3M; as of 2025-12-31.
KPTI-OWNER-T-ROWE-PRICE-INVESTMENT-MANAGEMENT-INC T. Rowe Price Investment Management, Inc. 95% 13F/ownership overlay lists T. Rowe Price Investment Management, Inc.; shares held 1,491,409; ownership 8.13%; value $8.2M; as of 2025-12-31.
KPTI-OWNER-OPALEYE-MANAGEMENT-INC Opaleye Management Inc. 95% 13F/ownership overlay lists Opaleye Management Inc.; shares held 930,000; ownership 5.07%; value $5.1M; as of 2025-12-31.
KPTI-OWNER-SOLEUS-CAPITAL-MANAGEMENT-L-P Soleus Capital Management, L.P. 95% 13F/ownership overlay lists Soleus Capital Management, L.P.; shares held 440,000; ownership 2.40%; value $2.4M; as of 2025-12-31.
KPTI-OWNER-AFFINITY-ASSET-ADVISORS-LLC Affinity Asset Advisors, Llc 95% 13F/ownership overlay lists Affinity Asset Advisors, Llc; shares held 889,575; ownership 4.85%; value $4.9M; as of 2025-12-31.
KPTI-OWNER-DAVIDSON-KEMPNER-CAPITAL-MANAGEMENT-LP Davidson Kempner Capital Management LP 95% 13F/ownership overlay lists Davidson Kempner Capital Management LP; shares held 310,020; ownership 1.69%; value $1.7M; as of 2025-12-31.
KPTI-OWNER-EXOME-ASSET-MANAGEMENT-LLC Exome Asset Management LLC 95% 13F/ownership overlay lists Exome Asset Management LLC ; shares held 295,541; ownership 1.61%; value $1.6M; as of 2025-12-31.
KPTI-OWNER-IKARIAN-CAPITAL-LLC Ikarian Capital, LLC 95% 13F/ownership overlay lists Ikarian Capital, LLC; shares held 544,554; ownership 2.97%; value $3.0M; as of 2025-12-31.

Karyopharm Therapeutics Inc. Extended Supply Chain Network

TickerNameChain IndexHopsRelationship Types
VSA VisionSys AI Inc. 100.00 2
BBIO BridgeBio Pharma, Inc. 100.00 2
KREF KKR Real Estate Finance Trust Inc. 100.00 2
NVSEF Novartis AG 100.00 2
EYE National Vision Holdings, Inc. 100.00 2
ANL Adlai Nortye Ltd. 100.00 2
IRON Disc Medicine, Inc. 100.00 2
KKR KKR & Co. Inc. 100.00 1 ['customer']
SNYNF Sanofi 100.00 2
GLTO Damora Therapeutics, Inc. 100.00 1 ['supplier']
MRK Merck & Co., Inc. 100.00 2
ORANY ORANGE 100.00 1 ['customer', 'supplier']
CYCN Cyclerion Therapeutics, Inc. 50.00 2
AYTU Aytu BioPharma, Inc. 50.00 2
ASBPW Aspire Biopharma Holdings, Inc. 50.00 2
ARQQW Arqit Quantum Inc. 50.00 2
CPRX Catalyst Pharmaceuticals, Inc. 50.00 2
BLTE Belite Bio, Inc 50.00 2
AUMN Golden Minerals Company 50.00 2
AMZE Amaze Holdings, Inc. 50.00 2
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KPTI
Unlock KPTI Supply Chain Data
Verified relationships include:
THIRD-PARTY-CONTRACT-MANUFACTURERSTHIRD-PARTY-CONTRACT-MANU…Supplier92%
ADVERTISING-AGENCIESADVERTISING-AGENCIESSupplier90%
ANTENGENE-THERAPEUTICS-LIMITEDANTENGENE-THERAPEUTICS-LIMITEDCustomer90%
BERLIN-CHEMIE-AGBERLIN-CHEMIE-AGCustomer90%
+27 more relationships locked
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