8Suppliers
17Customers
2Debt Items
20Related Chains

Source-Backed Evidence Depth

Upstream Bio, Inc. (UPB) is shown with relationship data already present in ChainSifter's database. Counts below come from stored supply-chain records and filing/source URLs where available; missing source URLs are not filled in or estimated.

28Total relationships
3Distinct source URLs
8High confidence
0.729Average confidence
2026-09-13Latest database update
ChainSifter does not infer unreported suppliers, customers, ownership, acquisitions, debt exposure, revenue dependency, or future supply-chain events on this public page.

Upstream Bio, Inc. Suppliers

TickerNameConfidenceEvidence
LEERINK-PARTNERS-LLC LEERINK-PARTNERS-LLC 92% On March 26, 2026, Upstream Bio, Inc. (the “Company”) entered into a Sales Agreement (the “Sales Agreement”) with Leerink Partners LLC, as sales agent (the “Agent”), pursuant to which the Company fro…
ASTELLAS-PHARMA-INC ASTELLAS-PHARMA-INC 90% Pursuant to the Astellas Asset Purchase Agreement, we purchased from Astellas the compound designated by Astellas as ASP7266
REGN Regeneron Pharmaceuticals, Inc. 80% Reciprocal relationship from REGN graph: Reciprocal relationship from UPB graph: Reciprocal relationship from REGN graph: Reciprocal relationship from UPB graph: Reciprocal relationship from REGN gra…
REGN Regeneron Pharmaceuticals, Inc. 80% The Regeneron Letter Agreement relates to a prior Non-Exclusive License and Material Transfer Agreement that Regeneron and Astellas entered into
AZN AstraZeneca PLC 72% ise such that they may be more successful than us in obtaining regulatory approval and achieving widespread market acceptance. • We expect to expand our organization, and as a result, we may encounte…
AZN AstraZeneca PLC 72% Reciprocal relationship from AZN graph: Reciprocal relationship from UPB graph: Reciprocal relationship from AZN graph: Reciprocal relationship from UPB graph: Reciprocal relationship from AZN graph:…
SNYNF Sanofi 72% or development of AI technologies. In addition, various federal regulators have issued guidance and focused enforcement efforts on the use of AI in regulated sectors. The FDA, for example, issued dra…
SNYNF Sanofi 72% Reciprocal relationship from SNYNF graph: Reciprocal relationship from UPB graph: or development of AI technologies. In addition, various federal regulators have issued guidance and focused enforceme…

Upstream Bio, Inc. Customers

TickerNameConfidenceEvidence
MARUHO MARUHO 90% The Company concluded that Maruho is a customer under the Maruho Agreement, and as such, the Maruho Agreement falls within the scope of ASC 606
MYGN Myriad Genetics, Inc. 72% Reciprocal relationship from MYGN graph: Reciprocal relationship from UPB graph: liability or toxic tort claims that may be asserted against us in connection with our storage or disposal of biologica…
MYGN Myriad Genetics, Inc. 72% liability or toxic tort claims that may be asserted against us in connection with our storage or disposal of biological, hazardous or radioactive materials. In addition, we may incur substantial cost…
REGN Regeneron Pharmaceuticals, Inc. 72% llaboration arrangements with third parties. Until we can generate sufficient product revenue to finance our cash requirements, if ever, we expect to fund our operations through equity offerings or d…
REGN Regeneron Pharmaceuticals, Inc. 72% Reciprocal relationship from REGN graph: Reciprocal relationship from UPB graph: llaboration arrangements with third parties. Until we can generate sufficient product revenue to finance our cash requ…
SNYNF Sanofi 72% or development of AI technologies. In addition, various federal regulators have issued guidance and focused enforcement efforts on the use of AI in regulated sectors. The FDA, for example, issued dra…
SNYNF Sanofi 72% Reciprocal relationship from SNYNF graph: Reciprocal relationship from UPB graph: Reciprocal relationship from SNYNF graph: Reciprocal relationship from UPB graph: or development of AI technologies. …
ASTELLAS-PHARMA-INC ASTELLAS-PHARMA-INC 62% ntinue to incur significant financial losses for the foreseeable future. We are a clinical-stage biopharmaceutical company with a limited operating history. We were formed in April 2021 and our opera…
DELAWARE-GENERAL-CORPORATION DELAWARE-GENERAL-CORPORATION 62% Even if we are successful in defending against such claims, litigation could result in substantial costs and distract our technical and management personnel from their normal responsibilities. In add…
HONG-KONG-LIMITED HONG-KONG-LIMITED 62% could jeopardize or invalidate our intellectual property or proprietary information or expose us to potential litigation; • collaborators may infringe the intellectual property rights of third partie…
KONG-LIMITED KONG-LIMITED 62% g Kong) Limited to manufacture the Compound, requiring us to pay a mid-six-figure annual fee to Lonza pursuant to this provision. Any royalties due under the Lonza License Agreement are payable on a …
LEERINK-PARTNERS-LLC LEERINK-PARTNERS-LLC 62% rch 31, 2025. The increase of $1.3 million was primarily driven by an increase in personnel expenses of $0.7 million due to increased headcount in our general and administrative functions. Personnel …
LONZA-SALES-AG LONZA-SALES-AG 62% llaboration arrangements with third parties. Until we can generate sufficient product revenue to finance our cash requirements, if ever, we expect to fund our operations through equity offerings or d…
MARUHO-CO-LTD MARUHO-CO-LTD 62% e continue to make investments to improve the protection of data and information technology, including in the hiring of information technology (“IT”) personnel, periodic cyber security awareness trai…
PLAB Photronics, Inc. 62% Reciprocal relationship from PLAB graph: Reciprocal relationship from UPB graph: liability or toxic tort claims that may be asserted against us in connection with our storage or disposal of biologica…
PROMETHEUS-LABORATORIES-INC PROMETHEUS-LABORATORIES-INC 62% liability or toxic tort claims that may be asserted against us in connection with our storage or disposal of biological, hazardous or radioactive materials. In addition, we may incur substantial cost…
REGENERON-PHARMACEUTICALS-INC REGENERON-PHARMACEUTICALS-INC 62% ntinue to incur significant financial losses for the foreseeable future. We are a clinical-stage biopharmaceutical company with a limited operating history. We were formed in April 2021 and our opera…

Upstream Bio, Inc. Debt Obligations

InstrumentDescriptionConfidenceEvidence
UPB-DEBT Debt stack $1.1M 90% Market cache reports total debt of $1.1M.
UPB-DEBT-13229 Xbrl Convertible 90% xbrl convertible detail from xbrl 2024-09-30.

Upstream Bio, Inc. Acquisitions

No acquisitions on recordNo completed or pending acquisitions found in our database for Upstream Bio, Inc..

Upstream Bio, Inc. Ownership

HolderNameConfidenceEvidence
UPB-OWNER-FMR-LLC FMR LLC 90% 13F overlay lists FMR LLC as top holder; 144 tracked holders.

Upstream Bio, Inc. Extended Supply Chain Network

TickerNameChain IndexHopsRelationship Types
DBVTF DBV TECHNOLOGIES 100.00 2
ATOS Atossa Therapeutics, Inc. 100.00 2
CHRS Coherus Oncology, Inc. 100.00 2
ANL Adlai Nortye Ltd. 100.00 2
SVA Sinovac Biotech Ltd. 100.00 2
EDIT Editas Medicine, Inc. 100.00 2
CYTOF Altamira Therapeutics Ltd. 100.00 2
BLRX BioLineRx Ltd. 100.00 2
BIOA BioAge Labs, Inc. 100.00 2
CYTK Cytokinetics, Incorporated 100.00 2
CBIO Crescent Biopharma, Inc. 100.00 2
ANRO Alto Neuroscience, Inc. 100.00 2
BNBX BNB Plus Corp. 100.00 2
CCEP Coca-Cola Europacific Partners PLC 100.00 2
DSGN Design Therapeutics, Inc. 100.00 2
AZN AstraZeneca PLC 100.00 2 ['supplier']
EDSA Edesa Biotech, Inc. 100.00 2
ALXO ALX Oncology Holdings Inc. 100.00 2
PSNL Personalis, Inc. 100.00 2
BNTC Benitec Biopharma Inc. 100.00 2
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UPB
Unlock UPB Supply Chain Data
Verified relationships include:
LEERINK-PARTNERS-LLCLEERINK-PARTNERS-LLCSupplier92%
ASTELLAS-PHARMA-INCASTELLAS-PHARMA-INCSupplier90%
MARUHOMARUHOCustomer90%
MYGNMyriad Genetics, Inc.Customer72%
+24 more relationships locked
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